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Septic thrombophlebitis results from extensive infection of the lateral pharyngeal space to the jugular vein and generally occurs in healthy adolescents and young adults. This disease can disseminate to multiple distant sites such as joint, liver, kidney, eye, bone, and especially lung, and can lead patients into fatal condition. Contrast enhanced computed tomography and ultrasonography are good diagnostic methods for external jugular vein thrombophlebitis (EJVT). Treatment of EJVT includes intravenous antibiotics and surgical drainage of abscess, ligation or excision of the jugular vein, in addition to fibrinolytic agents and anticoagulants. With a review of literature, authors report a case of external jugular vein thrombophlebitis with sepsis which has successfully been managed by ligation and excision of the vein.
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